Commerce Kids is open Monday–Friday, 7:15 AM–5:45 PM, year round.
Each year the Board of Directors sets the Center's operating calendar, usually in December for the coming year. The operating calendar tells the days on which Commerce Kids will be either closed, or open on a short schedule. Commerce Kids is always closed on Federal holidays, and the Board sets aside other days each year for training or other purposes. The Center may also open on a shortened daily schedule during periods of low attendance, especially between Christmas and New Year's.
Below are the days when the Center will be either closed, or open on a reduced schedule:
| Monday, January 2 | Closed | New Year's Day Observed |
| Monday, January 16 | Closed | Martin Luther King Jr.'s Birthday |
| Friday, February 17 | Closed to students | Staff Development |
| Monday, February 20 | Closed | Washington's Birthday |
| Friday, May 25 | Closed to students | Staff Development |
| Monday, May 28 | Closed | Memorial Day |
| Wednesday, July 4 | Closed | Independence Day |
| Friday, August 31 | Closed to students | Staff Development |
| Monday, September 3 | Closed | Labor Day |
| Monday, October 8 | Closed | Columbus Day |
| Friday, November 9 | Closed to students | Staff Development |
| Monday, November 12 | Closed | Veterans Day |
| Thursday, November 22 | Closed | Thanksgiving Day |
| Friday, November 23 | Closed | Day after Thanksgiving |
| Tuesday, December 25 | Closed | Christmas Day |
| Wednesday, December 26 - Monday, December 31 | Open 8 AM - 5 PM | Winter Holiday Hours |
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